What are the consequences of the lack of Choline?

If we are in the lack of long-term intake of dietary choline may include the main findings of the liver, kidney, pancreas disease, memory disorders and growth failure.
Liver changes: most of the animals (other than ruminants outside) the lack of choline cause liver dysfunction, a large number of liver lipid (mainly triglyceride) accumulation and eventually filled the entire liver cells.
Kidney changes: lack also harmful to the kidneys shrink cholinergic function.
Induced cancer: lack of choline caused by genetic damage caused by carcinogenic process first, and then some can form tumor cell survival and proliferation of variations.